Sunday, December 22, 2019

The Effects Of Dependence On High Dosages Of Benzodiazepines

As the Rolling Stones called them in their hit song, â€Å"Mother’s Little Helper†, â€Å"Mother needs something today to calm her down, and though she s not really ill, there s a little yellow pill, she goes running for the shelter of a mother s little helper, and it helps her on her way, gets her through her busy day†, benzodiazepines were and extremely common medication in the 70s and 80s and many households had their bottle of Valium. The dependence on high dosages of benzodiazepines such as Xanax and Valium are a major clinical concern. According to Michael Liebrenz of the University of Bern, â€Å"This form of dependence is not confined to users who exceed a set amount of diazepam equivalents, but is typically found in patients who have a high-dose, long-term and/or otherwise problematic use, such as mixing BZDs, escalating dosage, using BZDs for recreational purposes, obtaining them by illegal means, and/or experiencing negative social consequences† (Liebrenz, 2016, p. 1). So the problem is not only found in patients who take large dosages, but in patients who also abuse the drug, combine multiple types of benzodiazepines and other drugs, and purchase them illegally in order to be under the influence of a benzodiazepine. This is why, for the last decade, less and less prescriptions of benzodiazepines have been dispensed in the United States. However, â€Å"over the last 20 years the quantity of benzodiazepines on each prescription has increased† (Brett, 2015, p. 152). BenzodiazepinesShow MoreRelatedThe Drug And Therapy During The U.s. Withdrawal Treatment2024 Words   |  9 PagesHigh dosages of benzodiazepines creates a massive clinical concern as patients can be easily dependent. Benzodiazepines are an incredibly abused drug in the U.S. Withdrawal treatment is recommended; however, it is sometimes unsuccessful for a large portion of patients. While ceasing the administration the drug all at once can be incredibly difficult for the patient and often times detrimental to the patient’s health, tapering is recommended by most doctors for allowing patients to successfully beRead MoreDrugs and Society Essay925 Words   |  4 Pagesoriginating cell or be metabolized within the synapse. 2b. Differentiate between drug disposition tolerance, behavioral tolerance, and pharmacodynamics tolerance, and provide reasons why these concepts should be taken into account when determining the effects of a drug. Drug disposition tolerance is defined as the increase of the drug’s rate of metabolism or removal. The user may increase the amount of a drug taken due to the drug being metabolized too quickly or being removed from the body. A personRead MoreGabapentin Versus Lorazepam: Which Drug Is More Effective in the Treatment of Alcohol Withdrawal?1096 Words   |  5 Pageschallenge has been to identify medications that not only reduce the rewarding effects of alcohol, but the dependence, post cessation craving, and the withdrawal craving. Lorazepam and gabapentin have been used for the detoxification of alcohol dependent patients. Lorazepam is a type of benzodiazepine, an antianxiety medication. Gabapentin is a type of anticonvulsant drug originally used to prevent seizures. â€Å"Benzodiazepines represent the standard of care for the treatment of alcohol withdrawal† (MyrickRead MoreCategories of Primarily Generalized and Partial Seizures1191 Words   |  5 Pagesmovements or hallucinate (McKean, 2012). Plan The patient is admitted to the Intensive Care Unit (ICU). Close monitoring for any refractory seizure activity, if seizure activity occurs and persists for five minutes or longer promptly treat with a Benzodiazepine preferably lorazepam or midazolam (Dionisio, 2012). While in the ICU T.L will receive valproic acid at maintenance dose of 15 to 20 mg/kg day given in eight hour intervals and is initiated six hours after the initial loading dose. Next, an EEGRead MorePrescription Drug Abuse Essay1744 Words   |  7 Pagesdrug and will need to seek out more or higher dosages of the drug to obtain the same effect. When seeking out larger doses, and more of the opiods, the user will face an increased possibility of side effects. Some of the side effects when some abuses opiods are nausea, vomiting, restlessness, anxiety, diarrhea, respiratory problems such as slow or arrested breathing, lowered pulse and blood pressure, unconsciousness, coma, and even death. Long term effects of opiod u se that create the euphoria to withdrawalRead MoreAlcoholism Outline809 Words   |  4 Pages  Classification and terminology of Alcoholism A. Etymology II. History of Alcohol III. Signs and symptoms B.   Symptoms of long term alcohol misuse 1. Physical symptoms 2. Psychiatric symptoms 3.   Social effects C. Alcohol withdrawal IV. Causes of Alcoholism D. Genetic variation V. Pathophysiology VI. Diagnosis of Alcoholism E. Social barriers F. Screening G. Genetic predisposition testing H. DiagnosticRead MoreMerck, Sharpe And Dohme Corp1595 Words   |  7 Pagesdate: August 13, 2014 FDA rating: New Molecular Entity (NME) Standard drug approval (S) Many current sleep aides target gamma-aminobutyric acid (GABA) receptors in the brain which can cause unwanted side effects like next day time sedation, rebound insomnia and physical or psychological dependence. Belsomra is being reviewed due to the unique mechanism of action focusing on efficacy and safety profile. Pharmacology and Indications Suvorexant is FDA indicated for insomnia (falling asleep and stayingRead MoreMedications Essay1741 Words   |  7 PagesAnxiolytic/Hypnotic: Benzodiazepines: Valium (Diazepam), Librium (Chlordiazepoxide), Xanax (Alprazolam), Clonazepam (Klonopin), Clorazeptate (Tranxene), Estazolam (ProSom), Eszopiclone (Lunesta), Flurazepam (Dalmane), Lorazepam (Ativan), Oxazepam (Serax), Quazepam (Doral), Temazepam (Restoril), Triazolam (Halcion) Comment: These medications have potent anxiolytic, sedative, muscle relaxant, anti-convulsant and amnestic properties. When administered intravenously or in high doses, benzodiazepines may produceRead MoreADVANCE Individual and Group Counseling,Diagnosis and Assessment of the Addicted Client.4613 Words   |  19 PagesCounseling Methadone Clients Using Benzodiazepines And other Licit and Illicit Substance Case Scenario: Michael Doe is a 21 year old methadone patient. He presented at a Methadone Treatment Center with a 3 year history of opioid prescription use (egg. Percocet). A) What is Methadone? (1 page) B) Purpose of Methadone: Primary and Side effects (2 Pages) C) History of Methadone Use in the United States (1 Page) D) The Synergistic Effects of Methadone and Benzodiazepines/ Other licit and licit Drugs (3Read MoreDrug And Medicine Of The Medical Field And Classification Of Medicine1368 Words   |  6 Pagesmolecules, natural products or educators were checked in right cells or whole creatures to identify substances that have a required therapeutic effect in a process known as classical pharmacology. Since sequencing of the human genome which allowed rapid cloning and synthesis of large quantities of purified proteins, it has become common practice to use high throughput screening of large compounds libraries against isolated biological targets which are hypothesized to be disease modifying in a process

No comments:

Post a Comment

Note: Only a member of this blog may post a comment.